Secretariat Time Programme
Daily
12:00 - 13:30

sfe

Fousteris Manolis
Tel. : (+302610)   962391 / 962392
Fax. : (+302610)   969182

E-mailThis e-mail address is being protected from spambots. You need JavaScript enabled to view it  



Current Position
Assistant Professor in Medicinal Chemistry, Department of Pharmacy, University of Patras, Greece.

 

Education
2000: Diploma in Pharmacy, University of Patras, Greece
2002: M.Sc. in Medicinal Chemistry, University of Patras, Greece
2005: Ph.D. in Medicinal Chemistry, University of Patras, Greece
2005: Postdoctoral Researcher, CNRS - Université de Reims Champagne-Ardenne, Unité Mixte de Recherche No 6519-Réactions Sélectives et Applications, “Catalyse” Group.
2006-2007: Postdoctoral Researcher, Laboratory of Medicinal Chemistry, Department of Pharmacy, University of Patras, Greece.
2007-2008: Postdoctoral Researcher, Institute of Organic Chemistry, Department of Chemistry and Mineralogy, University of Leipzig, Germany.

Research Interests

  • Design and synthesis of small heterocycIic molecules as potential protein kinase inhibitors.
  • Design, synthesis and evaluation of the biological activity of new steroidal alkylating agents.
  • Design, synthesis and structure-activity relationship studies of novel steroidal derivatives with anticancer activity.

Participation in Recent Research Projects

  • DESMI 2008, Republic of Cyprus and the European Regional Development Fund.
    “Design, Synthesis and Biological Evaluation on Cardiovascular System of New Selective
    Inhibitors of Soluble Guanyl Cyclase”. Duration time: 2008-2010.
    Research Coordinator (Cyprus): Associate Prof. Panayotis Koutentis
    Research Coordinator (Greece): Associate Prof. Sotiris Nikolaropoulos Research Scientist
  • Research Grant “Κ. Κaratheodori (C.109)”, Research Committee, University of Patras, Greece.
    “Design, Synthesis and Biological Evaluation of Novel Pyrrolo- Indolo-azepinone Derivatives as Potential Inhibitors of the Cyclin Dependent Kinase 1 (CDK1)”. Duration time: 2010-2013.
    Research Coordinator: Dr. M. Fousteris
  • Hrakleitos II, Ministry of Education-Hellenic Republic, European Union-FP7
    “Design, Synthesis and Biological Evaluation of New Indole Derivatives, Analogues of Natural Products as Potential Protein Kinase Inhibitors”. Duration time: 2011-2014.
    Research Coordinator: Associate Prof. Sotiris Nikolaropoulos
    Research Scientist

Publications
Papers in peer-reviewed international journals: 26
Abstracts in proceedings of international conferences: 12
Abstracts in proceedings of national conferences: 54

Professional Affiliations

  • Hellenic Society of Medicinal Chemistry
  • European Federation of Medicinal Chemistry

Teaching Activities

Undergraduate Courses

Undergraduate Program-Department of Pharmacy
Synthetic Organic Chemistry (32Y211-3rd Semester)
Lectures: S. Nikolaropoulos, G. Pairas, M. Fousteris
Practical Course: C. Camoutsis, P. Magriotis, S. Nikolaropoulos, G. Pairas, M. Fousteris

Medicinal Chemistry I (32Y221-4th Semester)
Lectures: S. Nikolaropoulos, M. Fousteris
Practical Course: C. Camoutsis, P. Magriotis, S. Nikolaropoulos, G. Pairas, M. Fousteris

Medicinal Chemistry IV (32Y413-7th Semester)
Lectures: G. Pairas
Practical Course: C. Camoutsis, P. Magriotis, S. Nikolaropoulos, G. Pairas, M. Fousteris

Postgraduate Courses

Postgraduate Program in “Pharmaceutical Sciences and Technology”, Department of Pharmacy-University of Patras
Modern Approaches in Medicinal Chemistry (ΦΜ-Α03)
C. Camoutsis, P. Magriotis, S. Nikolaropoulos, G. Pairas, M. Fousteris

Advanced Topics in Organic Synthesis (ΦΜ-Α04)
P. Cordopatis, V. Magafa, P. Magriotis, S. Nikolaropoulos, M. Fousteris

Drug Design (ΦΜ-Α07)
S. Nikolaropoulos, G. Pairas, G. Patrinos, C. Poulas, G. Spyroulias, S. Tzartos, M. Fousteris

Interdepartmental Postgraduate Program in “Medicinal Chemistry”, Department of Chemistry and Pharmacy-University of Patras
Practical Course in Medicinal Chemistry (ΕΦΧ 200)
V. Magafa, S. Nikolaropouloς, M. Fousteris

Selected Publications

  1.  E. Lampropoulou, M. Manioudaki, M. Fousteris, A. Koutsourea, S. Nikolaropoulos, E. Papadimitriou. Pyrrolo[2,3-α]carbazole derivatives as topoisomerase I inhibitors that affect viability of glioma and endothelial cells in vitro and angiogenesis in vivo. Biomedicine and Pharmacotherapy 2011, 65, 142-150.
  2. M. A. Fousteris, U. Schubert, D. Roell, J. Roediger, N. Bailis, S. S. Nikolaropoulos, A. Baniahmad, A. Giannis. 20-Aminosteroids as a novel class of selective and complete androgen receptor antagonists and inhibitors of prostate cancer cell growth. Bioorganic & Medicinal Chemistry 2010, 18, 6960-6969.
  3. F. Churruca, M. Fousteris, Y. Ishikawa, M. Von Wantoch Rekowski, C. Hounsou, T. Surrey, A. Giannis: A novel approach to indoloditerpenes by nazarov photocyclization: Synthesis and biological investigations of terpendole E analogues. Organic Letters 2010, 12, 2096-2099.
  4. K. Spyridonidou, M. Fousteris, M. Antonia, A. Chatzianastasiou, A. Papapetropoulos, S. Nikolaropoulos. Tricyclic indole and dihydroindole derivatives as new inhibitors of soluble guanylate cyclase. Bioorganic & Medicinal Chemistry Letters 2009, 19, 4810-4813.
  5. M. A. Fousteris, A. Papakyriakou, A. Koutsourea, M. Manioudaki, E. Lampropoulou, E. Papadimitriou, G. A. Spyroulias, S. S. Nikolaropoulos. Pyrrolo[2,3-a]carbazoles as potential cyclin dependent kinase 1 (CDK1) inhibitors. Synthesis, biological evaluation, and binding mode through docking simulations. Journal of Medicinal Chemistry 2008, 51, 1048-1052.

Student Office Hours:
Monday, 10:00-13:00
Thursday, 10:00-13:00