The Secretariat accepts students on weekdays from 12:00 - 13:30

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Study Guide 2019-20

Pairas George

Tel.: (+30) 2610 962327  Office
        (+30) 2610 962360  Lab./Post Graduate Students
Fax: (+30) 2610 969182
E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
             This e-mail address is being protected from spambots. You need JavaScript enabled to view it

Office Hours for Postgraduate Students
[Winter Semester 2019-2020]
   Tuesday, Wednesday & Friday:  11:00-13:00
[Spring Semester 2019-2020]
   Tuesday, Wednesday:  11:00-13:00 & Thursday:   09:00-11:00

 

Education

1987: Ph.D. in Medicinal Chemistry, University of Patras, Greece 
1982: Bachelor' Degree in Pharmacy, University of Patras, Greece

Scientific Field

Design - Synthesis - SAR & QSAR - Conformational Studies of Bioactive Compounds

Research Interests

  • Natural & Modified Steroids - Design and Synthesis of Ester and Amide derivatives - -Evaluation of Possible Anti-tumor Activity
  • Heterocyclic Compounds - Bioactive Building Blocks in Heterocyclic Synthesis
  • Drugs against Infections
  • Peptides & Polypeptides - Synthesis - Conformational Studies

Recent Research Papers

  • “Synthesis of Novel Sulfonamide-1,2,4-Triazoles, 1,3,4-Thiadiazoles and 1,3,4-Oxadiazoles, as Potential Antibacterial and Antifungal Agents. Biological Evaluation and Conformational Analysis Studies” P. Zoumpoulakis, Ch. Camoutsis, G. Pairas, M. Soković, J. Glamočlija, C. Potamitis and A. Pitsas; Bioorganic & Medicinal Chemistry, 20 (2012) 1569 
  • “Zn(II) Pyridyloxime Complexes as Potential Reactivators of OP-Inhibited Acetylcholinesterase: 
In vitro and Docking Simulation Studies” K. F. Konidaris, G. A. Dalkas, E. Katsoulakou, G. Pairas, C. P. Raptopoulou, F. N. Lamari, G. A. Spyroulias and E. Manessi-Zoupa; Journal of Inorganic Biochemistry, 134 (2014) 12 
  • “Potentiation by Caffeine of Cytogenetic Damage Induced by Steroidal Derivatives in Human Lymphocytes In vitro” C. Mourelatos, S. Nikolaropoulos, M. Fousteris, G. Pairas, M. Argyraki, D. Lykidis, S. Fidanic, D. Mourelatos and T. Lialiaris; Mutat Res Genet Toxicol Environ Mutagen. 766 (2014) 
  • “NMR Conformational Dynamics of an Anthrax Lethal Factor Domain Studied by Multiple Amino Acid-Selective Labeling” D. J. Vourtsis, C. T. Chasapis, G. Pairas, D. Bentrop and G. A. Spyroulias; Biochemical and Biophysical Research Communications, 450(1) (2014) 335 
  • “Structural Studies and Cytotoxicity Assays of “Aggregation-Prone” IAPP8-16 and its Non-Amyloidogenic Variants Suggest its Important Role in Fibrillogenesis and Cytotoxicity of Human Amylin (hIAPP)” N. N. Louros, P. L. Tsiolaki, A. A. Zompra, E. V. Pappa, V. Magafa, G. Pairas, P. Cordopatis, 
C. Cheimonidou, I. P. Trougakos, V. A. Iconomidou, S. J. Hamodrakas; 
Biopolymers (Peptide Science), 104(3) (2015) 196 
  • “H-Bond: The Chemistry & Biology H bridge” G.N. Pairas and P. G.Tsoungas;  
Chemistry Select, 1(15) (2016) 4520-453 
  • “The Isoxazole Ring and its N-oxide: A Privileged Structure in Neuropsychiatric Therapeutics” G. Pairas, F. Perperopoulou, P. G. Tsoungas and G. Varvounis; ChemMedChem., 2017, 12(6), 408-417 

Further Details: Curriculum Vitæ [September 2019]