Secretariat Time Programme
Daily
12:00 - 13:30

sfe

Pairas George

Tel. : (+302610) 962327  --  962360
Fax : (+30261) 969182
E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it This e-mail address is being protected from spambots. You need JavaScript enabled to view it


Education
1987: Ph.D. in Pharmaceutical Chemistry, University of Patras, Greece
1982: Bachelor' Degree in Pharmacy, University of Patras, Greece

 

Scientific Field
Design - Synthesis - SAR & QSAR - Conformational Studies of Bioactive Compounds

Research Interests

  • Natural & Modified Steroids - Design and Synthesis of Ester and Amide derivatives - -Evaluation of Possible Anti-tumor Activity
  • Heterocyclic Compounds - Bioactive Building Blocks in Heterocyclic Synthesis
  • Drugs against Infections
  • Peptides & Polypeptides - Synthesis - Conformational Studies
Positions’ Overview
  • ABBOTT LABORATORIES HELLAS: Athens  Greece  1987-1989
  • UNIVERSITY OF PATRAS: Dept of Pharmacy  Lecturer  Medicinal Chemistry  1989
  • UNIVERSITY OF PATRAS: Dept of Pharmacy Assist. Professor (short term)  Medicinal Chemistry  1993
  • UNIVERSITY OF PATRAS: Dept of Pharmacy  Assist. Professor  Medicinal Chemistry  1998
  • UNIVERSITÄT LEIPZIG SABBATICAL  Inst für Organische Chemie  Organische Chemie und Naturstoffchemie  Prof. Dr. A. Giannis: Oct 2012 - Mar 2013
  • UNIVERSITY OF PATRAS: Dept of Pharmacy  Assoc. Professor  Medicinal Chemistry  2015

Teaching Activities

UNDERGRADUATE COURSES

  • 1st Semester: " Intro to Pharmaceutical Sciences"
  • 2nd Semester: "Classic Analytical Chemistry"
  • 3rd Semester: "Lab. Courses in General & Analytical Chemistry"
  • 7th Semester: "Pharmaceutical Chemistry IV: Drugs against Infections"
  • 9th Semester: "Bioethics & Legislation", "Pharmaceutical Practice I"
  • 10th Semester: "Pharmaceutical Care”
GRADUATE COURSES
  • “Drug Design” - - “Drug Discovery & MedicoMarketing” Dept of Pharmacy - UPatras Departmental PostGraduate Prog.: Pharmaceutical Sciences & Technology
  • "Pharmaceutical Products of Natural & Synthetic Origin" Depts. of Chemistry, Pharmacy & Medicine - UPatras Joint PostGraduate Prog.: Medicinal Chemistry: Drug Design & Development
  • "Introduction to Pharmaceutical Sciences" Depts. of Medicine, Pharmacy, Biology & Physics - UPatras Joint PostGraduate Prog.: Informatics for Life Sciences
  •  “Medicinal Chemistry” Depts. of Chemistry, Pharmacy & Medicine - UPatras Joint PostGraduate Prog.: Chemical Biology

Publications
Books in english (Transl & co.Ed.) 5, in greek 2.
Peer-Reviewed International Journals (Research papers): 39
Peer–Reviewed International Journals & Books (Conference papers): 22
International Conferences Communications: 24
National Conferences Publications (Proceedings): 25
National Conferences Communications (Abstracts in greek): 52

Recent Research Papers

  • “Xanthones in Heterocyclic Synthesis. An Efficient and General Route for the Synthesis of Regioselectively Substituted Phthalazines” Y. Gardikis, P. Tsoungas, C. Potamitis, G. Pairas, M. Zervou and P. Cordopatis. Heterocycles, 83, (2011) 1291.
  • “Synthesis of Novel Sulfonamide-1,2,4-Triazoles, 1,3,4-Thiadiazoles and 1,3,4-Oxadiazoles, as Potential Antibacterial and Antifungal Agents. Biological Evaluation and Conformational Analysis Studies” P. Zoumpoulakis, Ch. Camoutsis, G. Pairas, M. Soković, J. Glamočlija, C. Potamitis and A. Pitsas. Bioorganic & Medicinal Chemistry, 20 (2012) 1569.
  • “Steroidal esters of the aromatic nitrogen mustard 2-[4-N,N-bis(2- chloroethyl)amino-phenyl]butanoic acid (2-PHE-BU): Synthesis and in-vivo biological evaluation” I. C. Papaconstantinou, M. A. Fousteris, A. I. Koutsourea, G. N. Pairas, A. D. Papageorgiou and S. S. Nikolaropoulos. Anti-Cancer Drugs, 24(1) (2013), 52.
  • ZnII Pyridyloxime Complexes as Potential Reactivators of OP-Inhibited Acetylcholinesterase: 
In vitro and Docking Simulation Studies” K. F. Konidaris, G. A. Dalkas, E. Katsoulakou, G. Pairas, C. P. Raptopoulou, F. N. Lamari, G. A. Spyroulias and E. Manessi-Zoupa. Journal of Inorganic Biochemistry, 134 (2014) 12.
  • “Potentiation by Caffeine of Cytogenetic Damage Induced by Steroidal Derivatives in Human Lymphocytes In vitro” C. Mourelatos, S. Nikolaropoulos, M. Fousteris, G. Pairas, M. Argyraki, D. Lykidis, S. Fidanic, D. Mourelatos and T. Lialiaris. Mutat Res Genet Toxicol Environ Mutagen. 766 (2014)
  • “Structural Studies and Cytotoxicity Assays of “Aggregation-Prone” IAPP8-16 and its Non-Amyloidogenic Variants Suggest its Important Role in Fibrillogenesis and Cytotoxicity of Human Amylin (hIAPP)” N. N. Louros, P. L. Tsiolaki, A. A. Zompra, E. V. Pappa, V. Magafa, G. Pairas, P. Cordopatis, C. Cheimonidou, I. P. Trougakos, V. A. Iconomidou, S. J. Hamodrakas. Biopolymers (Peptide Science), 104(3) (2015) 196.

FULL CV