The Secretariat accepts students on weekdays from 12:00 - 13:30

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Study Guide 2019-20

Poulas Konstantinos
Tel. : (+30) 2610 962353
         (+30) 2610 962354
Fax : (+30) 2610 969955
E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it

Recent CV

Education

 2001: PhD in Biology, Department of Biology, University of Athens, GREECE
1993: Diploma in Biology, University of Athens, GREECE

Research Activities

  • Construction, expression and purification of recombinant proteins
  • Electronic nicotine delivery systems - Toxicology
  • Cannabinoids - in vivo and in vitro studies
  • Innovative crystallization of proteins
  • Electroceuticals in health and food
  • Bioinformatics and medical informatics
Publications: 90
Patents: 5
H-index = 25
Citations = 2200

Professional Affiliations
  • Greek Society of Biochemistry and Molecular Biology
  • Hellenic Crystallographic Association
  • HBIO - Hellenic Cluster of Biotechnology

Publications 2012 - 2019

2019
Lagoumintzis G, Zagoriti Z, Jensen MS, Argyrakos T, Koutsojannis C, Poulas K.  Direct Microampere Current in Wound Healing: Clinical and Immunohistological Data from Two Single Case Reports. Biosensors (Basel). 2019 Sep 5;9(3).
Lampos S, Kostenidou E, Farsalinos K, Zagoriti Z, Ntoukas A, Dalamarinis K, Savranakis P, Lagoumintzis G, Poulas K. Time Assessment of E-Cigarettes and Conventional Cigarettes Emissions: Aerosol Size Distributions, Mass and Number Concentrations. Toxics. 2019 Aug 30;7(3).
Farsalinos K, Siakas G, Poulas K, Voudris V, Merakou K, Barbouni A.E-cigarette use is strongly associated with recent smoking cessation: an analysis of a representative population sample in Greece. Intern Emerg Med. 2019 Jan 14.
Wirsing P. Konstantakaki M, Poulas K. Martorell’s ulcer successfully treated by Wireless Microcurrent Stimulation technology. Advances in Skin and Wound Care. 2019 Feb; 32(2) 81-84.

2018
Farsalinos K, Yannovits N, Sarri T, Voudris V, Poulas K, Leischow S.  Carbonyl emissions from a novel heated tobacco product (IQOS): comparison with an e-cigarette and a tobacco cigarette. Addiction. 2018 Nov. 113(11): 2099-2106.
Kouretas D, Tsatsakis A, Poulas K. Editorial: Alternative tobacco products: Toxicology and health issues. Food Chem Toxicol. 2018 May 26. pii: S0278-6915(18)30356-9.
Konstantinou E, Fotopoulou F, Drosos A, Dimakopoulou N, Zagoriti Z, Niarchos A, Makrynioti D, Kouretas D, Farsalinos K, Lagoumintzis G, Poulas K. Tobacco-specific nitrosamines: A literature review. Food Chem Toxicol. 8;118:198-203.
Farsalinos KE, Siakas G, Poulas K, Voudris V, Merakou K, Βarbouni A. Electronic cigarette use in Greece: an analysis of a representative population sample in Attica prefecture. Harm reduction journal. 13;15(1):20.
Zagoriti Z, Lagoumintzis G, Perroni G, Papathanasiou G, Papadakis A, ... Poulas K. Evidence for association of STAT4 and IL12RB2 variants with Myasthenia gravis susceptibility: What is the effect on gene expression in thymus? Journal of Neuroimmunology. 319, 93-99.
Kamilari E, Farsalinos K, Poulas K, Kontoyannis CG, Orkoula M. Detection and quantitative determination of heavy metals in electronic cigarette refill liquids using Total Reflection X-ray Fluorescence Spectrometry. Food and Chemical Toxicology. 116(Pt B):233-237
El Mubarak M, Danika C, Vlachos N, Farsalinos K, Poulas K, Sivolapenko G. Development and validation of analytical methodology for the quantification of aldehydes in e-cigarette aerosols using UHPLC-UV. Food and Chemical Toxicology. 116(Pt B):147-151

2017
Farsalinos KE, Poulas K, Voudris V. Changes in puffing topography and nicotine consumption depending on the power setting of electronic cigarettes. Nicotine and Tobacco Research. (Impact factor: 4.6   - Citations: ) 2018 Jul 9; 20(8): 993-997.
Niarchos A, Lagoumintzis G, Poulas K. TA-GC cloning: a new simple and versatile technique for the directional cloning of PCR products for recombinant protein expressionPLoS One. 12(11), e0186568
Hatzis Y, Thireou T, Viennas E, Atlamazoglou V, Papadopoulos G, Poulas K, Eliopoulos E, Tzimas J. RGDtrip: A Database for the Investigation of Proteins Containing the RGD Tripeptide. Current Bioinformatics. In press
Farsalinos KE, Voudris V, Spyrou A, Poulas K. E-cigarettes emit very high formaldehyde levels only in conditions that are aversive to users: A replication study under verified realistic use conditions. Food Chem Toxicol. 109:90-94.
Farsalinos KE, Yannovits N, Sarri T, Voudris V, Poulas K. Nicotine delivery to the aerosol of a heat-not-burn tobacco product: comparison with a tobacco cigarette and e-cigarettes. Nicotine Tob Res. 2017 Jun 16. doi: 10.1093/ntr/ntx138.
Farsalinos KE, Poulas K, Voudris V, Le Houezec J. Prevalence and correlates of current daily use of electronic cigarettes in the European Union: analysis of the 2014 Eurobarometer survey. Intern Emerg Med. 12(6), 757-763.
Farsalinos KE, Poulas K, Voudris V, Le Houezec J.E-cigarette use in the European Union: millions of smokers claim e-cigarettes helped them quit. Addiction. 2017 Mar;112(3):545-546.

2016
Balasopoulou A, Stanković B, Panagiotara A, Nikčevic G, Peters BA, John A, Mendrinou E, Stratopoulos A, Legaki AI, Stathakopoulou V, Tsolia A, Govaris N, Govari S, Zagoriti Z, Poulas K, Kanariou M, Constantinidou N, Krini M, Spanou K, Radlovic N, Ali BR, Borg J, Drmanac R, Chrousos G, Pavlovic S, Roma E, Zukic B, Patrinos GP, Katsila T. Novel genetic risk variants for pediatric celiac disease. Hum Genomics. 24;10(1):34.
Jelastopulu E, Fafliora E, Plota A, Babalis V, Bartsokas C, Poulas K, Plotas P. Knowledge, behaviours and attitudes regarding HPV infection and its prevention in female students in West Greece. Eur Rev Med Pharmacol Sci. 20(12):2622-9.
Farsalinos KE, Poulas K, Voudris V, Le Houezec J. Electronic cigarette use in the European Union: analysis of a representative sample of 27 460 Europeans from 28 countries. Addiction. 111(11):2032-2040.
Farsalinos KE, Yannovits N, Sarri T, Voudris V, Poulas K. Protocol proposal for, and evaluation of, consistency in nicotine delivery from the liquid to the aerosol of electronic cigarettes atomizers: regulatory implications. Addiction. 111(6):1069-76.

2015
Niarchos A, Lagoumintzis G, Poulas K. Utilizing the virus-induced blocking of apoptosis in an easy baculovirus titration method. Sci Rep. 5:15487.
Farsalinos KE, Gillman G, Poulas K, Voudris V. Tobacco-Specific Nitrosamines in Electronic Cigarettes: Comparison between Liquid and Aerosol Levels. Int J Environ Res Public Health. 12(8):9046-53.
Farsalinos KE, Spyrou A, Stefopoulos C, Tsimopoulou K, Kourkoveli PTsiapras DKyrzopoulos SPoulas KVoudris V. Nicotine absorption from electronic cigarette use: comparison between experienced consumers (vapers) and naïve users (smokers). Sci Rep. 5:11269. doi: 10.1038/srep11269.
Farsalinos KE, Voudris V, Poulas K. E-cigarettes generate high levels of aldehydes only in 'dry puff' conditions. Addiction. 110(8):1352-6
Farsalinos KE, Voudris V, Poulas K. Are metals emitted from electronic cigarettes a reason for health concern? A risk-assessment analysis of currently available literature. Int J Environ Res Public Health. 12(5):5215-32.
Yilmaz V, Oflazer P, Aysal F, Durmus H, Poulas K, Yentur SP, Gulsen-Parman Y, Tzartos S, Marx A, Tuzun E, Deymeer F, Saruhan-Direskeneli G. Differential Cytokine Changes in Patients with Myasthenia Gravis with Antibodies against AChR and MuSK. PLoS One. 10(4):e0123546.
Farsalinos KE, Gillman IG, Melvin MS, Paolantonio AR, Gardow WJ, Humphries KE, Brown SE, Poulas K, Voudris V. Nicotine levels and presence of selected tobacco-derived toxins in tobacco flavoured electronic cigarette refill liquids. Int J Environ Res Public Health. 12(4):3439-52.

2014
Boltsis I, Lagoumintzis G, Chatzileontiadou D, Giastas P, Tzartos SJ, Leonidas D, Poulas K. Non-contact Current Transfer Induces the Formation and Improves the X-ray Diffraction Quality of Protein Crystals Cryst. Growth Des., 2014, 14 (9), pp 4347–4354
Kambouris M, Zagoriti Z, Lagoumintzis G, Poulas K. From therapeutic Electrotherapy to Electroceuticals: Formats, Applications and Prospects of Electrostimulation. Annual Research & Review in Biology, ISSN: 2347-565X,Vol.: 4, Issue.: 20 (16-31 October)
Michail G, Smaili M, Vozikis A, Jelastopulu E, Adonakis G, Poulas K. Female students receiving post-secondary education in Greece: the results of a collaborative human papillomavirus knowledge survey. Public Health. 128(12):1099-105.
Avidan N, Le Panse R, Harbo HF, Bernasconi P, Poulas K, Ginzburg E, Cavalcante P, Colleoni L, Baggi F, Antozzi C, Truffault F, Horn-Saban S, Pöschel S, Zagoriti Z, Maniaol A, Lie BA, Bernard I, Saoudi A, Illes Z, Casasnovas Pons C, Melms A, Tzartos S, Willcox N, Kostera-Pruszczyk A, Tallaksen C, Mantegazza R, Berrih-Aknin S, Miller A. VAV1 and BAFF, via NFκB pathway, are genetic risk factors for myasthenia gravis. Ann Clin Transl Neurol. 1(5):329-39.
Gkantouna VA, Kambouris ME, Viennas ES, Ioannou ZM, Paraskevas M, Lagoumintzis G, Zagoriti Z, Patrinos GP, Tzimas GE, Poulas K. Introducing dAUTObase: a first step towards the global scale geoepidemiology of autoimmune syndromes and diseases. Bioinformatics. 31(4):581-6.
Kordas G, Lagoumintzis G, Sideris S, Poulas K, Tzartos SJ. Direct proof of the in vivo pathogenic role of the AChR autoantibodies from myasthenia gravis patients. PLoS One. 9(9):e108327.
Dalabira E, Viennas E, Daki E, Komianou A, Bartsakoulia M, Poulas K, Katsila T, Tzimas G, Patrinos GP. DruGeVar: an online resource triangulating drugs with genes and genomic biomarkers for clinical pharmacogenomics. Public Health Genomics. 17(5-6):265-71.
Kouvatsos N, Niarchos A, Zisimopoulou P, Eliopoulos E, Poulas K, Tzartos S. Purification and functional characterization of a truncated human α4β2 nicotinic acetylcholine receptor. Int J Biol Macromol. 70:320-6.
Ulusoy C, Kim E, Tüzün E, Huda R, Yılmaz V, Poulas K, Trakas N, Skriapa L, Niarchos A, Strait RT, Finkelman FD, Turan S, Zisimopoulou P, Tzartos S, Saruhan-Direskeneli G, Christadoss P. Preferential production of IgG1, IL-4 and IL-10 in MuSK-immunized mice. Clin Immunol. 151(2):155-63.

2013
Lagoumintzis G, Zisimopoulou P, Trakas N, Grapsa E, Poulas K, Tzartos SJ. Scale up and safety parameters of antigen specific immunoadsorption of human anti-acetylcholine receptor antibodies. J Neuroimmunol. 15;267(1-2):1-6.
Niarchos A, Zouridakis M, Douris V, Georgostathi A, Kalamida D, Sotiriadis A, Poulas K, Iatrou K, Tzartos SJ. Expression of a highly antigenic and native-like folded extracellular domain of the human α1 subunit of muscle nicotinic acetylcholine receptor, suitable for use in antigen specific therapies for Myasthenia Gravis. PLoS One. 8(12):e84791.
Zagoriti Z, Kambouris ME, Patrinos GP, Tzartos SJ, Poulas K. Recent advances in genetic predisposition of myasthenia gravis. Biomed Res Int. 2013:404053.
Papadopoulos P, Viennas E, Gkantouna V, Pavlidis C, Bartsakoulia M, Ioannou ZM, Ratbi I, Sefiani A, Tsaknakis J, Poulas K, Tzimas G, Patrinos GP. Developments in FINDbase worldwide database for clinically relevant genomic variation allele frequencies. Nucleic Acids Res. 2014 Jan;42(Database issue):D1020-6.
Tafrali C, Paizi A, Borg J, Radmilovic M, Bartsakoulia M, Giannopoulou E, Giannakopoulou O, Stojiljkovic-Petrovic M, Zukic B, Poulas K, Stavrou EF, Lambropoulou P, Kourakli A, Felice AE, Papachatzopoulou A, Philipsen S, Pavlovic S, Georgitsi M, Patrinos GP. (2013). Genomic variation in the MAP3K5 gene is associated with β-thalassemia disease severity and hydroxyurea treatment efficacy, Pharmacogenomics; 14(5):469-83.
Castana O, Dimitrouli A, Argyrakos T, Theodorakopoulou E, Stampolidis N, Papadopoulos E, Pallantzas A, Stasinopoulos I and Poulas K. (2013). Wireless Electrical Stimulation: An Innovative Powerful Tool for the Treatment of a Complicated Chronic Ulcer, The International Journal of Lower Extremity Wounds; 12:18-21.
Ramadhinara A, Poulas K. (2013). Use of wireless microcurrent stimulation for the treatment of diabetes-related wounds: 2 case reports, Adv Skin Wound Care; 26(1):1-4.
Kambouris M, Velegraki A, Patrinos GP, Poulas K. Biosecurity threats about the combination of aerobiology, morphology and genetic manipulation of fungal spores. Journal of life sciences. 7(2), 131.

2012
Lazaridis K, Zisimopoulou P, Lagoumintzis G, Skriapa L, Trakas N, Evangelakou P, Kanelopoulos I, Grapsa E, Poulas K, Tzartos S. (2012). Antigen-specific apheresis of autoantibodies in myasthenia gravis, Ann N Y Acad Sci; 1275(1):7-12.
Giannopoulou E, Bartsakoulia M, Tafrali C, Kourakli A, Poulas K, Stavrou EF, Papachatzopoulou A, Georgitsi M, Patrinos GP. (2012). A single nucleotide polymorphism in the HBBP1 gene in the human β-globin locus is associated with a mild β-thalassemia disease phenotype, Hemoglobin; 36(5):433-45.
Zagoriti Z, Georgitsi M, Giannakopoulou O, Ntellos F, Tzartos SJ, Patrinos GP, Poulas K. (2012). Genetics of myasthenia gravis: a case-control association study in the Hellenic population, Clin Dev Immunol; 48:491-9.
Poulas K, Katsouraki E, Kordas G, Kokla A, Tzartos SJ*. (2012). Anti-MuSK- and anti-AChR-positive myasthenia gravis induced by D-penicillamine, Journal of Neuroimmunology; 250(1-2):94-8
Viennas E, Gkantouna V, Ioannou M, Georgitsi M, Rigou M, Poulas K, Patrinos GP, Tzimas GE. (2012). Population-Ethnic Group Specific Genome Variation Allele Frequency Data: A Querying and Visualization Journey, Genomics; 100:93-101
Haidinis V, Dalkas G, Poulas K, Spyroulias G (2012) Molecular Modeling and Conformational Analysis of MuSK Protein. AIAI (2) 2012: 642-650
Gkantouna V, Ioannou ZM, Tsakalidis A, Viennas E, Poulas K, Tsaknakis J,Tzimas J. (2012). Towards an era of epidemiological databases for autoimmune diseases. BIBE 2012: 69-73

OFFICE HOURS FOR POSTCRADUATE STUDENTS
Monday , Tuesday, Thursday  11:00-13:00