Secretariat Time Programme
Daily
12:00 - 13:30

sfe

Poulas Konstantinos
Tel. : (+302610) 962353 | 962354
Fax : (+302610) 969-955
E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it

 

 

Education
2001: PhD in Biology, Department of Biology, University of Athens, GREECE
1993: Diploma in Biology, University of Athens, GREECE

Research Activities
  • Construction, expression and purification of recombinant protein fragments
  • Molecular genetics and molecular diagnosis
  • Structural studies of proteins
  • Epidemiology of myasthenia gravis and autoimmunity
  • Bioinformatics and medical informatics 

Research interests:

  • Autoimmunity
  • Myasthenia gravis
  • Gene expression
  • Protein characterization
  • Protein crystallization
  • Wound healing
  • Electroceuticals
He works with various methodologies in order to trace/identify/explore the binding sites of substrates to proteins and to map interaction interfaces. He has long lasting experience in myasthenia gravis pathogenesis and diagnosis. The last three years he is also working with a new scientific area, called ELECTROCEUTICALS. He is studying the effect of WMCS technology on wound healing and burns. He has about 50 publications in peer reviewed journals and he is currently participating in FP7 and national projects. Publications

International Journals and Books: 18
Abstracts of Conferences: 15

Professional Affiliations

  • Greek Society of Biochemistry and Molecular Biology
  • Hellenic Crystallographic Association
Prizes
  • 1998: Award of the 24th Panhellenic Medical Symposium
  • 1999: Prize “Looking to the future” during the Eurojunction ’99 conference
  • 2002: Archimedes Prize winner (44.000 Euros)

Recent Selected Publications

  • Kordas G, Lagoumintzis G, Sideris S, Poulas K, Tzartos SJ. Direct Proof of the In Vivo Pathogenic Role of the AChR Autoantibodies from Myasthenia Gravis Patients. PLoS One. 2014 Sep 26;9(9):e108327. doi: 10.1371/journal.pone.0108327. eCollection 2014.
  • Gkantouna VA, Kambouris ME, Viennas ES, Ioannou ZM, Paraskevas M, Lagoumintzis G, Zagoriti Z, Patrinos GP, Tzimas GE, Poulas K. Introducing dAUTObase: a first step towards the global scale geoepidemiology of autoimmune syndromes and diseases. Bioinformatics. 2014 Oct 20. pii: btu690. [Epub ahead of print]
  • Kambouris M, Zagoriti Z, Lagoumintzis G, Poulas K. From therapeutic Electrotherapy to Electroceuticals: Formats, Applications and Prospects of Electrostimulation. Annual Research and Review in Biology 2014, 4(20):3054-70.
  • Niarchos A, Zouridakis M, Douris V, Georgostathi A, Kalamida D, Sotiriadis A, Poulas K, Iatrou K, Tzartos SJ. Expression of a Highly Antigenic and Native-Like Folded Extracellular Domain of the Human α1 Subunit of Muscle Nicotinic Acetylcholine Receptor, Suitable for Use in Antigen Specific Therapies for Myasthenia Gravis. PLoS One. 2013 Dec 20;8(12):e84791. doi: 10.1371/journal.pone.0084791. eCollection 2013.
  • Papadopoulos P, Viennas E, Gkantouna V, Pavlidis C, Bartsakoulia M, Ioannou ZM, Ratbi I, Sefiani A, Tsaknakis J, Poulas K, Tzimas G, Patrinos GP. Developments in FINDbase worldwide database for clinically relevant genomic variation allele frequencies. Nucleic Acids Res. 2014 Jan 1;42(1):D1020-6.
  • Castana O, Dimitrouli A, Argyrakos T, Theodorakopoulou E, Stampolidis N, Papadopoulos E, Pallantzas A, Stasinopoulos I and Poulas K. (2013). Wireless Electrical Stimulation: An Innovative Powerful Tool for the Treatment of a Complicated Chronic Ulcer, The International Journal of Lower Extremity Wounds; 12:18-21.
  • Ramadhinara A, Poulas K. (2013). Use of wireless microcurrent stimulation for the treatment of diabetes-related wounds: 2 case reports, Adv Skin Wound Care; 26(1):1-4.
  • Zagoriti Z, Georgitsi M, Giannakopoulou O, Ntellos F, Tzartos SJ, Patrinos GP, Poulas K. (2012). Genetics of myasthenia gravis: a case-control association study in the Hellenic population, Clin Dev Immunol; 48:491-9.
  • Poulas K, Katsouraki E, Kordas G, Kokla A, Tzartos SJ. (2012). Anti-MuSK- and anti-AChR-positive myasthenia gravis induced by D-penicillamine, Journal of Neuroimmunology; 250(1-2):94-8
  • Georgitsi M, Viennas E, Gkantouna V, van Baal S, Petricoin EF, Poulas K, Tzimas G, Patrinos GP. (2010). FINDbase: A worldwide database for genetic variation allele frequencies updated, Nucleic Acids Research; 39(Database issue):D926-32
  • Lagoumintzis G, Poulas K, Patrinos GP. (2010). Genetic databases and their potential in pharmacogenomics, Curr Pharm Des; 16(20):2224-31.
  • Lagoumintzis G, Zisimopoulou P, Kordas G, Lazaridis K, Poulas K, Tzartos SJ. (2010). Recent approaches to the development of antigen-specific immunotherapies for myasthenia gravis, Autoimmunity; 43(5-6):436-45.
  • Kalamida D, Poulas K, Avramopoulou V, Fostieri E, Lagoumintzis G, Lazaridis K, Sideri A and Tzartos S. (2007). Muscle and Neuronal Nicotinic Acetylcholine Receptors: Structure, Function and Pathogenicity. FEBS Journal, 274 3799–3845.
  • Poulas K, Eliopoulos E, Vatzaki E, Navaza J, Kontou M, Oikonomakos N, Acharya KR and Tzartos SJ. (2001). Crystal structure of Fab198, an efficient protector of acetylcholine receptor against myasthenogenic antibodies, European Journal of Biochemistry; 268, 3685-3693.
  • Poulas K, Tsouloufis T and Tzartos SJ. (2000). Treatment of passively transferred experimental autoimmune myasthenia gravis using papain, Clinical and Experimental Immunology; 120:363-368.

DBLP CITED PUBLICATIONS

  • Haidinis V, Dalkas G, Poulas K, Spyroulias G (2012) Molecular Modeling and Conformational Analysis of MuSK Protein. AIAI (2) 2012: 642-650
  • Gkantouna V, Ioannou ZM, Tsakalidis A, Viennas E, Poulas K, Tsaknakis J,Tzimas J. (2012). Towards an era of epidemiological databases for autoimmune diseases. BIBE 2012: 69-73
  • Antoniou DI. Georgitsi M.A. Gkantouna V.A. Patrinos G.P. Poulas K. Tsakalidis AK. Tzimas G.E. Viennas E.S. (2010). dAUTObase: Mining gems on autoimmune diseases utilizing web visualization technologies ΙΤΑΒ 2010, 1-5
Ώρες υποδοχής Προπτυχιακών Φοιτητών 
Δευτέρα Τρίτη Τετάρτη 11-13 π.μ