Secretariat Time Programme
Daily
12:00 - 13:30

sfe

Laboratory of Instrumental Pharmaceutical Analysis

Laboratory of Instrumental Pharmaceutical Analysis

Personnel Faculty

 

Post-Doctoral Fellows

  • Dr. Petros Kokkinos, Biologist 

PhD Candidates

  • Panayiota Papaspyridakou, Pharmacist 
  • Stefani Fertaki, Chemical Engineer 
  • Michail Lykouras, Pharmacist 

Graduate Students

  • Anastasia Lygeraki, Pharmacist 
  • Panagiota Giannoutsou, Chemist 
  • Ioanna Chrisikou, Chemist 

Research Interests / Activities

Development of novel non-destructive analytical methodologies for:

  • The qualitative and quantitative determination of pharmaceutically active substances in pharmaceutical formulations (liquid or tablets), In biological fluids, for the study of drug release from micro- and nano-particles 
  • The characterization of polymorphic phases and generic drugs 
  • The study / monitoring of the chemical alterations caused during diseases of bone and cartilage (osteoporosis, osteoarthritis) 

Scientific Equipment

A list of the available instrumentation and the technical characteristics can be found here

Collaboration with Industry

Our lab collaborates with pharmaceutical companies Genepharm, Rontis, ELPEN, DEMO, Rafarm, OnePharma, Pharmathen, Pharos, Pharmadata, Verisfield UK, Famar, Lavipharm, Remedica (Cyprus), Synthon (Spain), Materia (Malta), Pharmacare Premium (Malta) for issues concerning:

  • Development of new formulations 
  • Testing of APIs polymorphism in tablets and creams 
  • Physicochemical characteristics testing 
  • Quantitative determination of active substances in biological fluids 

Publications in International Journals 

  • Karabas and Christos G. Kontoyannis “Characterization of calcium phosphates mixtures”, Vibrational Spectroscopy, 64 (2013) 126-133 (DOI 10.1007/s10856-012-4593-7). 
  • Karabas, M.G. Orkoula, C.G. Kontoyannis, “Calibration models for the quantitative analysis of bone (collagen and bioapatite) using raman spectroscopy”, J. Biophotonics, 6 (2013) 573-586 (doi 10.1002/jbio.201200053). 
  • Argyrios N. Nochos, Christos Kontoyannis, George G. Voyiatzis, “Incorporation of Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) in Poly(propylene) Matrices for Wound Healing Applications. The case of Ibuprofen” Macromol. Symp. 331-332 (2013) 115–122 (doi 0.1002/masy.201300093). 
  • Mohamed Ahmed S. El Mubarak, Fotini N. Lamari, Christos Kontoyannis, Simultaneous determination of allantoin and glycolic acid in snail mucus and cosmetic creams with high performance liquid chromatography and ultraviolet detection” Journal of Chromatography A, 1322 (2013) 49-53 (http://dx.doi.org/10.1016/j.chroma.2013.10.086). 
  • Malvina G. Orkoula and Christos G. Kontoyannis “Raman Spectroscopy for the Study of Biological Organisms (Biogenic Materials and Biological Tissues): A Valuable Analytical Tool”, Spectroscopy Europe, 26 (2014) 18-21. (Invited-review article) 
  • Harry Blair, Elena Kalyvioti, Nicholaos Papachristou, Irina Tourkova, Spryros Syggelos, Despina Deligianni, Malvina Orkoula, Christos Kontoyannis, Eleni Karavia, Kyriakos Kypreos, and Dionysios Papachristou, Laboratory Investigation, 96 (2016) 763-772 doi:10.1038/labinvest.2016.51 (2016) doi:10.1038/labinvest.2016.51. 
  • Georgia Tooulakou, Andreas Giannopoulos, Dimosthenis Nikolopoulos, Panagiota Bresta, Elissavet Dotsika, Malvina G. Orkoula, Christos G. Kontoyannis, Costas Fasseas, Georgios Liakopoulos, Maria I. Klapa, and George Karabourniotis, Plant Physiology, 171 (2016) 2577-2585 DOI:10.1104/pp.16.00111. 
  • Eleni Kamilari, Konstantinos Farsalinos, Konstantinos Poulas, Christos G. Kontoyannis, Malvina G. Orkoula, Food and Chemical Toxicology, 116, Part B, (2018) 233–237 https://doi.org/10.1016/j.fct.2018.04.035
  • Georgia Tooulakou, Andreas Giannopoulos, Dimosthenis Nikolopoulos, Panagiota Bresta, Elissavet Dotsika, Malvina G. Orkoula, Christos G. Kontoyannis, Costas Fasseas, Georgios Liakopoulos, Maria I. Klapa, and George Karabourniotis, “Reevaluation of the plant “gemstones”: Calcium oxalate crystals sustain photosynthesis under drought conditions”, Plant Signaling & Behavior, 11 (2016), NO. 9, e1215793 (4 pages) DOI: 10.1080/15592324.2016.1215793. 
  • Georgia Tooulakou, Dimosthenis Nikolopoulos, Elissavet Dotsika, Malvina G. Orkoula, Christos G. Kontoyannis, Georgios Liakopoulos, Maria I. Klapa, George Karabourniotis, Physiologia Plantarum, 2018, https://doi.org/10.1111/ppl.12843