The Secretariat accepts students on weekdays from 12:00 - 13:30


Study Guide 2019-20

DPHA_C01 Molecular Targets of Drug Action PDF Print

Instructors: E. Papadimitriou, G. Sotiropoulou, S. Topouzis

Co-ordinator: Ε. Papadimitriou


Cellular, biochemical and molecular pharmacology.
Drugs that act on receptors. Molecular structure of drug receptors.
Pharmacological targeting of ion channels.
Pharmacological targeting of G-protein coupled receptors.
Pharmacological targeting of receptors with endogenous catalytic actions (tyrosine and serine/threonine kinase, phosphatase, guanylate cyclase).
Pharmacological targeting of transcription factors.
Enzymes as drug targets.
Pharmacological targeting of secreted proteins (growth factors, cytokines).
Antisense oligonucleotides, siRNAs, aptamers and microRNAs as drugs.
Pharmacological targeting of signaling molecules.
Methods of identifying new drug targets.
Cell and gene therapies.
Optimization of production, stability and activity of protein drugs through biotechnological methods.
Development of experimental disease models with biotechnological / genetic methods in experimental animals.