The Laboratory of Molecular Biology and Immunology was created in 2003. Today, it has three faculty members who participate in 5 undergraduate and 5 post-graduate courses and supervise the research work of three post-doctoral fellows, three postgraduate students and the diploma work of several undergraduate students. We are in close collaboration with several Universities and Research Institutes, both national and international. We are performing research in aspects related to Immunology, Biochemistry, Molecular and Structural Biology, Genetics and Pharmacogenomics, which are funded from several research programs.
Research Team Faculty members Socrates Tzartos, Professor and Director (Immunobiology) (
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, tel: 2610 969955) George Patrinos, Assist. Prof. (Pharmacogenetics) (
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) Konstantinos Poulas, Assist. Prof. (Biochemistry) (
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, tel: 2610 969953) Post-Doctoral Researchers: 3 Graduate Students: 4
The Major Research Focus of the Laboratory is Vascular Pharmacology, specifically the molecular mechanisms of physiological and pathological angiogenesis such as that seen in cancer, the pathophysiology of vascular endothelial and smooth muscle cells, and the participation of the arterial wall in Inflammatory and Immune diseases. Research Team Faculty members Andreas Papapetropoulos, Professor and Director, email:
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Evangelia Papadimitriou, Associate Professor, e-mail:
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Stavros Topouzis, Assistant Professor, e-mail:
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Post-Doctoral Researchers: 2 Graduate Students: 15 (Ph.D. and M.Sc. students)
The Laboratory of Pharmacognosy & Chemistry of Natural Products of the Department of Pharmacy is well equipped and very active in synthesis and structure-activity studies on bioactive peptides, synthesis of heterocyclic scaffolds (e.g. non-natural amino acids) and isolation and characterization of natural products. Recently, the Laboratory has been certified by the TUV Rheinland Group, according to: DIN EN ISO 9001: 2000 for the establishment and application of a quality management system for "Research Process for the Design and the Development of Peptides and Other Biologically Active Compounds". The Laboratory collaborates with a large number of academic and industrial partners in Greece and abroad.
Research Team Faculty members Paul Cordopatis, Professor and Director, e-mail:
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Vassiliki Magafa, Assistant Professor, e-mail:
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Fotini Lamari, Assistant Professor, e-mail:
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Post-Doctoral Researchers: 4 Graduate Students: 10 (Ph.D. students:5 and M.Sc. students:5)
The laboratory has long-term experience in instrumental analysis, trace analysis and physicochemical characterization of materials/biomaterials. The group develops innovative analytical methods for detection, structural characterization, identification and quantitative analysis of materials of pharmaceutical and biomedical interest. It has experience in advanced spectroscopic, microscopic, chromatographic-mass spectrometric, electroanalytical and physicochemical characterization techniques. The group applies various methodologies for non-destructive, in-situ, on-line characterization and trace analysis of active pharmaceutical ingredients in formulations. The group is in constant collaboration with the Institute of Osteology (Vienna, Austria), the Institute of Chemical Engineering (ICE/HT-FORTH), the Bioanalytical Laboratory of Gaia Center and with a large number of Greek laboratories or teams.
Research Team Faculty members Christos Kontoyannis, Professor and Director, e-mail:
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Anthony Tsarbopoulos, Professor, e-mail:
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Malvina Orkoula, Lecturer, e-mail :
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Post-Doctoral Researchers: 1 Graduate Students: 5 (Ph.D. students: 1 and M.Sc. students: 4)
Research team Faculty member Klepetsanis Paulos, Assistant Professor, e-mail:
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The laboratory of pharmacokinetics focuses in the research and development activities related to drug development, namely in the optimization of the non clinical stage and the design and implementation of the early clinical development stages.
Research Team Faculty member Gregory Sivolapenko, Associate Professor, Tel.:+30 2610 969816, Fax: +30 2610 996302, email:
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Post-doctoral Researcher: 1 Graduate Students: 6 (Ph.D.: 3 and M.Sc. students: 3)
Advanced Drug Delivery System Group The group has long-term experience in technology, design and development of novel DDS, as nanosized liposomes and drug-cyclodextrin complexes, for advanced delivery and/or targeting of drugs, vaccines or genetic material. It has experience in advanced techniques for preparation and characterization of DDS and elucidation of interactions between drug molecules, cyclodextrins, lipids and polymers, in order to design the appropriate nanomedicine for each specific therapeutic need. Additionally system performance is evaluated in vitro and in vivo. The group collaborates with a large number of academic and industrial groups in Greece, Europe and USA.
Research Team Faculty member: Sophia G. Antimisiaris, Professor and Director, e-mail:
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Avgoustakis Konstantinos, Associate Professor, e-mail:
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Post-Doctoral Researchers: 3 Graduate Students: 11 (Ph.D. and M.Sc. students)
The laboratory has long-term experience in the field of anticancer agents. The research interest is focused in the design, synthesis and biological evaluation of new bioactive compounds with potential antitumor activity. Especially, modified steroidal derivatives, small heterocyclic compounds and natural products analogs (e.g. ecteinascidin/saframycin) are among the candidate synthetic targets. Members of the laboratory are in constant collaboration with Greek laboratories or teams in the University of Patras, in the Aristotle University of Thessaloniki and University of Athens as well as with members or teams of the National Hellenic Research Foundation in Athens. Also, members of the laboratory maintain research collaboration with partners in the EU. Our Laboratory has extensive experience in various chromatographic and spectrophotometric techniques for the purification and identification of all these compounds. Experience in drug design so that all these compounds turn out to be as active as possible (testing in collaboration with (Molecular) Biologists or Biochemists) toward the target (usually Receptor or Enzyme) and performing various reactions under inert conditions as needed, can also be considered as assets that our Laboratory can offer.
Website: www.pharmacy.upatras.gr
Research Team Faculty members Charalampos Camoutsis, Associate Professor and Director, e-mail:
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Plato Magriotis A., Associate Professor, e-mail:
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George Pairas, Assistant Professor, e-mail:
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Sotirios Nikolaropoulos, Assistant Professor, e-mail:
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Manolis Fousteris, Lecturer, e-mail:
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Graduate Students: 8 (Ph.D.: 3 and M.Sc. Students: 5)
Research